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Article

Analysis of the function of E. coli 23S rRNA helix-loop 69 by mutagenesis.

BMC molecular biology - 29 Jul 2005

Liiv Aivar, Karitkina Diana, Maiväli Ulo, Remme Jaanus

Abstract excerpt

BACKGROUND: The ribosome is a two-subunit enzyme known to exhibit structural dynamism during protein synthesis. The intersubunit bridges have been proposed to play important roles in decoding, translocation, and the peptidyl transferase reaction; yet the physical nature of their contributions is ill understood. An intriguing intersubunit bridge, B2a, which contains 23S rRNA helix 69 as a major component, has been...

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Identifiers

PMID: 16053518
DOI: 10.1186/1471-2199-6-18
PMCID: PMC1190176

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Analysis of the function of E. coli 23S rRNA helix-loop 69 by mutagenesis.PMID 16053518Read ↗

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