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Article

Vascular endothelial growth factor inhibits maturation of dendritic cells induced by lipopolysaccharide, but not by proinflammatory cytokines.

Cancer immunology, immunotherapy : CII - 1 Jun 2004

Takahashi Akihiro, Kono Koji, Ichihara Fumiko, Sugai Hidemitsu, Fujii Hideki, Matsumoto Yoshiro

Abstract excerpt

PURPOSE: Dendritic cells (DCs) play an important role in the host's immunosurveillance against cancer. It has been shown that the function of DCs is impaired and their population decreased in a cancer-bearing host. In the present study, we investigated the mechanism of down-regulation of DCs in a cancer-bearing host. METHODS: We evaluated the relationship between DC infiltration and production of vascular...

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Identifiers

PMID: 14666382
DOI: 10.1007/s00262-003-0466-8
PMCID: PMC11034272

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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