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Article

Interferon-gamma dose-dependently inhibits prostaglandin E2-mediated dendritic-cell-migration towards secondary lymphoid organ chemokines.

Vaccine - 30 Nov 2006

Alder John, Hahn-Zoric Mirjana, Andersson Bengt A, Karlsson-Parra Alex

Abstract excerpt

Monocyte-derived human dendritic cells (MoDCs) are increasingly applied as cellular vaccines for cancer patients. Important features for their efficacy include high migratory responsiveness to lymph node-chemokines and most likely their ability to produce bioactive IL-12 p70 upon subsequent contact with CD40 ligand-expressing T-cells. The current standard DC-maturation cocktail for clinical trials is inflammatory...

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Source

Identifiers

PMID: 16889876
DOI: 10.1016/j.vaccine.2006.07.002

Genes

CCR7
CCL19
CCL21
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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