Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vascular endothelial growth factor inhibits the function of human mature dendritic cells mediated by VEGF receptor-2.

Cancer immunology, immunotherapy : CII - 1 Jun 2007

Mimura Kousaku, Kono Koji, Takahashi Akihiro, Kawaguchi Yoshihiko, Fujii Hideki

Abstract excerpt

Dendritic cells (DCs) are the most potent antigen-presenting cells and play a central role in the host-antitumor immunity. Since it has been reported that vascular endothelial growth factor (VEGF) inhibits the functional maturation of immature-DCs and impairs DC differentiation, it is important to elucidate the mechanisms of VEGF-induced DC-dysfunction. To investigate the effects of VEGF against human mature DCs,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to Apoptosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Cells

Share to Flow Cytometry

Share to Interleukin-12

Share to Lymphocyte Culture Test, Mixed

Share to Vascular Endothelial Growth Factor A

Share to Vascular Endothelial Growth Factor Receptor-2

Source

Open in PubMed Open full text

Identifiers

PMID: 17086423
DOI: 10.1007/s00262-006-0234-7
PMCID: PMC11030780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Vascular endothelial growth factor inhibits the function of human mature dendritic cells mediated by VEGF receptor-2.PMID 17086423Read ↗

Vascular endothelial growth factor inhibits maturation of dendritic cells induced by lipopolysaccharide, but not by proinflammatory cytokines.Semantic proximity Read ↗

Dual role of VEGF family members in the pathogenesis of head and neck cancer (HNSCC): possible link between angiogenesis and immune tolerance.Semantic proximity Read ↗

Human dendritic cells engineered to express alpha tumor necrosis factor maintain cellular maturation and T-cell stimulation capacity.Semantic proximity Read ↗

Activation of human dendritic cells by recombinant modified vaccinia virus Ankara vectors encoding survivin and IL-2 genes in vitro.Semantic proximity Read ↗

Efficient migration of dendritic cells toward lymph node chemokines and induction of T(H)1 responses require maturation stimulus and apoptotic cell interaction.Semantic proximity Read ↗

Anti-P-selectin lectin-EGF domain monoclonal antibody inhibits the maturation of human immature dendritic cells.Semantic proximity Read ↗

Effects of glioma cells on maturation of dendritic cells.Semantic proximity Read ↗

In vitro analysis of the antileukemic effect of tumor necrosis factor-alpha gene therapy with myeloid progenitor cells: the role of dendritic cells.Semantic proximity Read ↗

Pigment-epithelium-derived factor (PEDF) inhibits angiotensin-II-induced vascular endothelial growth factor (VEGF) expression in MOLT-3 T cells through anti-oxidative properties.Semantic proximity Read ↗

Human allogeneic and murine xenogeneic dendritic cells are cytotoxic to human tumor cells via two distinct pathways.Semantic proximity Read ↗

Multiple drug resistance phenotype of human endothelial cells induced by vascular endothelial growth factor 165.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.