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Article

Tumor cells prevent mouse dendritic cell maturation induced by TLR ligands.

Cancer immunology, immunotherapy : CII - 1 Aug 2007

Idoyaga Juliana, Moreno José, Bonifaz Laura

Abstract excerpt

Tumor cells can evade the immune system through several mechanisms, one of which is to block DC maturation. It has been suggested that signaling via Toll-like receptors (TLR) may be involved in the induction of prophylactic anti-cancer immunity and in the treatment of established tumors. In the present study we found that high numbers of tumor cells interfere with BMDC activation induced by the TLR ligands LPS...

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Identifiers

PMID: 17237931
DOI: 10.1007/s00262-006-0275-y
PMCID: PMC11029892

Genes

TLR3
TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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