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Article

Induction of suppressive phenotype in monocyte-derived dendritic cells by leukemic cell products and IL-1β.

Human immunology - 1 Jul 2014

Motta Juliana Maria, Sperandio Aline, Castelo-Branco Morgana Teixeira Lima, Rumjanek Vivian Mary

Abstract excerpt

Professional antigen-presenting cells, dendritic cells (DCs) play an important role in controlling tumors. It is known that solid tumor cell products inhibit DC differentiation. Recently a similar effect produced by leukemic cell products has been demonstrated. In this case, leukemic cell products induced the secretion of IL-1β by monocytes undergoing differentiation. The aim of the present work was to...

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Identifiers

PMID: 24768898
DOI: 10.1016/j.humimm.2014.04.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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