Article
Differential maturation of murine bone-marrow derived dendritic cells with lipopolysaccharide and tumor necrosis factor-alpha.
Journal of endotoxin research - 1 Jan 2005
Efron Philip A, Tsujimoto Hironori, Bahjat Frances R, Ungaro Ricardo, Debernardis Justin, Tannahill Cynthia, Baker Henry V, Edwards Carl K, Moldawer Lyle L
Abstract excerpt
Dendritic cells (DCs) play a key role in the interface between the innate and acquired immune systems. In response to both exogenous as well as endogenous signals, DCs undergo a programmed maturation to become an efficient, antigen-presenting cell. Yet little is known regarding the differential responses by endogenous versus exogenous stimuli on DC maturation. In the present report, we have compared the...
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