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Article

Critical role for the Oct-2/OCA-B partnership in Ig-secreting cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2003

Salas Mabel, Eckhardt Laurel A

Abstract excerpt

B and T lymphocytes arise from a common precursor in the bone marrow, but ultimately acquire very different functions. The difference in function is largely attributable to the expression of tissue-specific transcription factors that activate discrete sets of genes. In previous studies we and others have shown that the specialized genes expressed by Ig-secreting cells cease transcription when these cells are...

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PMID: 14662861
DOI: 10.4049/jimmunol.171.12.6589

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