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Article

B-Cell coactivator OBF-1 exhibits unusual transcriptional properties and functions in a DNA-bound Oct-1-dependent fashion.

Molecular and cellular biology - 1 Jun 1999

Krapp A, Strubin M

Abstract excerpt

Eukaryotic transcriptional activators generally comprise both a DNA-binding domain that recognizes specific cis-regulatory elements in the target genes and an activation domain which is essential for transcriptional stimulation. Activation domains typically behave as structurally and functionally autonomous modules that retain their intrinsic activities when directed to a promoter by a variety of heterologous...

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Identifiers

PMID: 10330165
DOI: 10.1128/MCB.19.6.4247
PMCID: PMC104384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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B-Cell coactivator OBF-1 exhibits unusual transcriptional properties and functions in a DNA-bound Oct-1-dependent fashion.PMID 10330165Read ↗

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The Ets factor Spi-B is a direct critical target of the coactivator OBF-1.Semantic proximity Read ↗

The OBF-1 gene locus confers B cell-specific transcription by restricting the ubiquitous activity of its promoter.Semantic proximity Read ↗

Expression of the aldehyde dehydrogenase 2-like gene is controlled by BOB.1/OBF.1 in B lymphocytes.Semantic proximity Read ↗

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Using altered specificity Oct-1 and Oct-2 mutants to analyze the regulation of immunoglobulin gene transcription.Semantic proximity Read ↗

EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains.Semantic proximity Read ↗

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