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Article

The OBF-1 gene locus confers B cell-specific transcription by restricting the ubiquitous activity of its promoter.

European journal of immunology - 1 Oct 2003

Massa Steffen, Junker Steffen, Schubart Karin, Matthias Gabriele, Matthias Patrick

Abstract excerpt

Transcription of the gene encoding the transcriptional coactivator Oct-binding factor 1 (OBF-1)/OCA-B/Bob.1 is largely restricted to B cells. During B cell development OBF-1 expression shows two peaks, one in immature B cells in the bone marrow and the other in germinal center B cells. Promoter analysis has identified a cAMP response element (CRE)-binding site present in the OBF-1 proximal promoter that is...

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PMID: 14515270
DOI: 10.1002/eji.200323882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The OBF-1 gene locus confers B cell-specific transcription by restricting the ubiquitous activity of its promoter.PMID 14515270Read ↗

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