Article
B-cell deficiency and reduced B-cell reconstitution in hemoglobin-deficit mice.
Experimental hematology - 1 Dec 2003
Lipovsky Karen, Bennett Lori A, Chen Jichun
Abstract excerpt
OBJECTIVE: To study the effect of persistent hemoglobin-deficit mutation (hbd/hbd) on hematopoiesis and the function of hematopoietic stem cells (HSCs). METHODS: Young and old mice homozygous for the spontaneous hbd/hbd mutation were compared to young and old wild-type control mice, all on the C57BL/6 background, over cellular composition in blood and bone marrow (BM) using cell counting, complete blood counts,...
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