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Article

Engineering a dopaminergic phenotype in stem/precursor cells: role of Nurr1, glia-derived signals, and Wnts.

Annals of the New York Academy of Sciences - 1 May 2005

Arenas Ernest

Abstract excerpt

Recent results from clinical trials using fetal tissue grafts in patients with Parkinson's disease (PD) have indicated that current surgical strategies for dopamine cell replacement therapy need to be improved in order to achieve better functional integration of the grafts and to avoid dyskinesias. Previous studies using rich dopaminergic (DA) cell suspensions have provided proof-of-concept that PD patients can...

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Identifiers

PMID: 15965107
DOI: 10.1196/annals.1334.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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