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Article

Hyperactivated sperm motility driven by CatSper2 is required for fertilization.

Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 2003

Quill Timothy A, Sugden Sarah A, Rossi Kristen L, Doolittle Lynda K, Hammer Robert E, Garbers David L

Abstract excerpt

Elevations of sperm Ca2+ seem to be responsible for an asymmetric form of motility called hyperactivation, which is first seen near the time of fertilization. The mechanism by which intracellular Ca2+ concentrations increase remains unknown despite considerable investigation. Although several pro...

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Identifiers

PMID: 14657366
DOI: 10.1073/pnas.2136654100
PMCID: PMC299835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14657366-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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