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Quantification of CatSper1 expression in human spermatozoa and relation to functional parameters

15 May 2015

Abstract excerpt

STUDY QUESTION: Is CatSper1 expression in human spermatozoa related to semen parameter values and sperm functions? SUMMARY ANSWER: CatSper1 expression is positively related to progressive and hyperactivated (HA) motility, [Ca(2+)]i responsiveness to progesterone but not the acrosome reaction (AR). WHAT IS KNOWN ALREADY: The role of cationic channel of sperm (CatSper) in sperm functions is clear in animal models...

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PMID: 25983333
DOI: 10.1093/humrep/dev103

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