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Article

CatSper channel, sperm function and male fertility.

Reproductive biomedicine online - 1 Jan 2015

Singh Akhand Pratap, Rajender Singh

Abstract excerpt

A number of physiological events, such as sperm hyperactivation, chemotaxis towards the egg, capacitation and acrosome reaction, are triggered by activation of sperm ion channels in response to a diverse range of chemical cues. Cation channel of sperm (CatSper), a sperm-specific ion channel, is unique in orchestrating the events for fertilization, and seems to be exclusively evolved for sperm function and male...

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Source

Identifiers

PMID: 25457194
DOI: 10.1016/j.rbmo.2014.09.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CatSper channel, sperm function and male fertility.PMID 25457194Read ↗

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The Cation/Calcium Channel of Sperm (CatSper): A Common Role Played Despite Inter-Species Variation?Semantic proximity Read ↗

CatSper: The complex main gate of calcium entry in mammalian spermatozoaSemantic proximity Read ↗

Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivationSemantic proximity Read ↗

Calcium Signaling Through CatSper Channels in Mammalian FertilizationSemantic proximity Read ↗

Calcium Channels in the Development, Maturation, and Function of SpermatozoaSemantic proximity Read ↗

Unexplained infertility is frequently caused by defective CatSper function preventing sperm from penetrating the egg coatSemantic proximity Read ↗

Genetic male infertility and mutation of CATSPER ion channels.Semantic proximity Read ↗

The essential calcium channel of sperm CatSper is temperature-gatedSemantic proximity Read ↗

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