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Article

Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse.

Biology of reproduction - 1 Jul 2007

Jin Jingling, Jin Nange, Zheng Huili, Ro Seungil, Tafolla Dora, Sanders Kenton M, Yan Wei

Abstract excerpt

Catsper3 and Catsper4 are two recently identified testis-specific genes homologous to Catsper1 and Catsper2 that have been shown to play an essential role in sperm hyperactivated motility and male fertility in mice. Here we report that Catsper3 and Catsper4 knockout male mice are completely infertile due to a quick loss of motility and a lack of hyperactivated motility under capacitating conditions. Our data...

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Source

Identifiers

PMID: 17344468
DOI: 10.1095/biolreprod.107.060186

Genes

CATSPER3
CATSPER4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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