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The CatSper calcium channel in human sperm: relation with motility and involvement in progesterone-induced acrosome reaction

15 Jan 2014

Abstract excerpt

STUDY QUESTION: Does CatSper have a role in the achievement of human sperm motility and in the Progesterone (P)-induced acrosome reaction (AR)? SUMMARY ANSWER: CatSper1 expression is associated with human sperm progressive motility and the P-induced AR; it may have a role in the pathogenesis of asthenozoospermia. WHAT IS KNOWN ALREADY: Knockout mice for any of the Catsper family genes fail to acquire...

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PMID: 24430778
DOI: 10.1093/humrep/det454

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