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Article

CatSper1 required for evoked Ca2+ entry and control of flagellar function in sperm.

Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 2003

Carlson Anne E, Westenbroek Ruth E, Quill Timothy, Ren Dejian, Clapham David E, Hille Bertil, Garbers David L, Babcock Donner F

Abstract excerpt

CatSper family proteins are putative ion channels expressed exclusively in membranes of the sperm flagellum and required for male fertility. Here, we show that mouse CatSper1 is essential for depolarization-evoked Ca2+ entry and for hyperactivated movement, a key flagellar function. CatSper1 is n...

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Identifiers

PMID: 14657352
DOI: 10.1073/pnas.2536658100
PMCID: PMC299831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14657352-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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