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Article

Whole Mitochondrial Genome Analysis in Non-Small Cell Lung Carcinoma Reveals Unique Tumor-Specific Somatic Mutations.

Archives of pathology & laboratory medicine - 1 Nov 2023

Kim Moon-Young, Kim Hajin, Sung Jung-A, Koh Jaemoon, Cho Sohee, Chung Doo Hyun, Jeon Yoon Kyung, Lee Soong Deok

Abstract excerpt

CONTEXT.—: Mitochondria and mitochondrial DNA have been suggested to play a role in cancer initiation and progression. Knowledge of mitochondrial DNA could provide a breakthrough to advance cancer management. OBJECTIVE.—: To identify the mitochondrial DNA landscape in non-small cell lung carcinoma. DESIGN.—: The adenocarcinoma set consisted of 365 pairs of adenocarcinomas and normal lung tissues, whereas the...

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PMID: 36602894
DOI: 10.5858/arpa.2022-0175-OA

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