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Article

Alteration of the p53 gene during tree shrews' hepatocarcinogenesis.

Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Nov 2003

Su Jian-Jia, Li Yuan, Ban Ke-Chen, Qin Liu-Liang, Wang Hui-Yun, Yang Chun, Ou Chao, Duan Xiao-Xian, Lee Yl Young lk, Yan Rui-Qi

Abstract excerpt

OBJECTIVE: To detect the expression and variation of the p53 gene in hepatocarcinogenesis of tree shrews induced by hepatitis B virus (HBV) and aflatoxin B1 (AFB1). METHODS: Tree shrews were divided into four groups: group A, infected with HBV and fed with AFB1; group B, only infected with HBV; group C, fed with AFB1 alone; and group D normal control. The tree shrews underwent liver biopsy every 15 weeks. Liver...

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PMID: 14627531

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Source receipt: pubmed, retrieved 7 Sept 2026.

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