Article
TP53 and liver carcinogenesis.
Human mutation - 1 Mar 2003
Staib Frank, Hussain S Perwez, Hofseth Lorne J, Wang Xin W, Harris Curtis C
Abstract excerpt
Primary hepatocellular carcinoma (HCC) is one of the most common malignancies and has the fourth highest mortality rate worldwide. The major risk factors, including chronic infections with the hepatitis B or C virus, are exposure to dietary aflatoxin B1(AFB1), vinyl chloride, or alcohol consumption. Southern China and sub-Saharan Africa have the highest dietary AFB1 exposure, making it and hepatitis B virus (HBV)...
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