Article
[Alteration of p53 gene during tree shrews' hepatocarcinogenesis].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Mar 2003
Su Jian-jia, Li Yuan, Ban Ke-chen, Qin Liu-liang, Wang Hui-yun, Yang Chun, Ou Chao, Duan Xiao-xian, Li Yong-yi, Yan Rui-qi
Abstract excerpt
OBJECTIVE: To detect the expression and variation of p53 gene during tree shrews' hepatocarcinogenesis induced by hepatitis B virus (HBV) and aflatoxin B1 (AFB1). METHODS: Tree shrews were divided into four groups: the tree shrews were infected with HBV and fed with AFB1 in group A, only infected with HBV in group B, fed with AFB1 alone in group C, and normal control in group D. All the tree shrews were performed...
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