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Article

Hydroxyapatite accelerates differentiation and suppresses growth of MC3T3-E1 osteoblasts.

Journal of biomedical materials research. Part A - 15 Dec 2003

Shu R, McMullen R, Baumann M J, McCabe L R

Abstract excerpt

Hydroxyapatite describes both the natural mineral phase of bone as well as the widely used calcium-phosphate implant substitute. Given that hydroxyapatite is a major component of the in vivo surface with which osteoblasts interact, it is surprising that most studies examining the regulation of osteoblast growth and differentiation utilize plastic surfaces. Here we demonstrate that the phenotype of mouse MC3T3-E1...

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Identifiers

PMID: 14624506
DOI: 10.1002/jbm.a.20021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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