Article
Phenotype and gene expression pattern of osteoblast-like cells cultured on polystyrene and hydroxyapatite with pre-adsorbed type-I collagen.
Journal of biomedical materials research. Part A - 1 Nov 2007
Hanagata Nobutaka, Takemura Taro, Monkawa Akira, Ikoma Toshiyuki, Tanaka Junzo
Abstract excerpt
Hydroxyapatite and type-I collagen are major components of bone matrix. We compared phenotype and gene expression pattern of osteoblast-like cells cultured on HAp and HAp with pre-adsorbed type-I collagen from neutral solutions (HAp/NCs) with those of tissue culture grade polystyrene (TCPS) and TCPS with the collagen (TCPS/NCs). In initial cell attachment, the cells tensely spread on TCPS, while loosely spread on...
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