Article
Osteoblastic phenotype expression on the surface of hydroxyapatite ceramics.
Journal of biomedical materials research - 1 Oct 1997
Okumura M, Ohgushi H, Dohi Y, Katuda T, Tamai S, Koerten H K, Tabata S
Abstract excerpt
To analyze the bone-bonding property of hydroxyapatite ceramics (HA), composites of rat marrow cells and porous HA were implanted subcutaneously and harvested at 3 to 4 weeks postimplantation. De novo bone formation was observed primarily on the HA surface without fibrous tissue interposition. The HA/tissue interface was analyzed by the observations of thin undecalcified histological sections and fractured...
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