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Article

Concepts of osteoblast growth and differentiation: basis for modulation of bone cell development and tissue formation.

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists - 1 Jan 1992

Lian J B, Stein G S

Abstract excerpt

The combined application of molecular, biochemical, histochemical, and ultrastructural approaches has defined a temporal sequence of gene expression associated with development of the bone cell phenotype in primary osteoblast cultures. The peak levels of expressed genes reflect a developmental sequence of bone cell differentiation characterized by three principal periods: proliferation, extracellular matrix...

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PMID: 1571474
DOI: 10.1177/10454411920030030501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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