Article
Osteoblasts exhibit a more differentiated phenotype and increased bone morphogenetic protein production on titanium alloy substrates than on poly-ether-ether-ketone.
The spine journal : official journal of the North American Spine Society - 1 Mar 2012
Olivares-Navarrete Rene, Gittens Rolando A, Schneider Jennifer M, Hyzy Sharon L, Haithcock David A, Ullrich Peter F, Schwartz Zvi, Boyan Barbara D
Abstract excerpt
BACKGROUND CONTEXT: Multiple biomaterials are clinically available to spine surgeons for performing interbody fusion. Poly-ether-ether-ketone (PEEK) is used frequently for lumbar spine interbody fusion, but alternative materials are also used, including titanium (Ti) alloys. Previously, we showed that osteoblasts exhibit a more differentiated phenotype when grown on machined or grit-blasted titanium aluminum...
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