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Article

Rab23, a negative regulator of hedgehog signaling, localizes to the plasma membrane and the endocytic pathway.

Traffic (Copenhagen, Denmark) - 1 Dec 2003

Evans Timothy M, Ferguson Charles, Wainwright Brandon J, Parton Robert G, Wicking Carol

Abstract excerpt

The regulation of hedgehog signaling by vesicular trafficking was exemplified by the finding that Rab23, a Rab-GTPase vesicular transport protein, is mutated in open brain mice. In this study, the localization of Rab23 was analyzed by light and immunoelectron microscopy after expression of wild-type (Rab23-GFP), constitutively active Rab23 (Rab23Q68L-GFP), and inactive Rab23 (Rab23S23N-GFP) in a range of...

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Identifiers

PMID: 14617350
DOI: 10.1046/j.1600-0854.2003.00141.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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