Article
Open brain gene product Rab23: expression pattern in the adult mouse brain and functional characterization.
Journal of neuroscience research - 1 May 2006
Guo Anchen, Wang Ting, Ng Ee Ling, Aulia Selina, Chong Kooi Hoong, Teng Felicia Yu Hsuan, Wang Ya, Tang Bor Luen
Abstract excerpt
The gene mutated in the mouse open brain (opb) phenotype antagonizes sonic hedgehog-mediated signaling and encodes a small GTPase of the Rab family, Rab23. To date, the brain expression profile and exact mechanism of function of the Rab23 protein has remained unknown. Specific antibodies generated against Rab23 showed that the protein is highly enriched in the adult rodent brain and present in low levels in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
