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Article

Rab23: what exactly does it traffic?

Traffic (Copenhagen, Denmark) - 1 Jun 2006

Wang Ya, Ng Ee Ling, Tang Bor Luen

Abstract excerpt

Rab23 is the product of the gene mutated in the mouse open brain1 phenotype, which displays neural tube defects. It appears to antagonize sonic hedgehog (Shh)-mediated signaling during mouse development, presumably by regulating the intracellular trafficking of one or more of Shh's-signaling components. The Shh receptor Patched1 (Ptch1) and its downstream effector Smoothened (Smo) were initial prime suspects as...

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Share to Cilia
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Share to Hedgehog Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to rab GTP-Binding Proteins

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Source

Identifiers

PMID: 16683919
DOI: 10.1111/j.1600-0854.2006.00416.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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