Article
Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane.
Molecular biology of the cell - 1 Nov 2007
Gomi Hiroshi, Mori Kenichi, Itohara Shigeyoshi, Izumi Tetsuro
Abstract excerpt
Rab proteins regulate multiple, complex processes of membrane traffic. Among these proteins, Rab27a has been shown to function specifically in regulated exocytic pathways. However, the roles of Rab27b, another Rab27 subfamily member, have not been well characterized. We disrupted the Rab27b gene in mice. The targeting vector was designed to insert LacZ downstream of the initiation codon of the Rab27b gene so that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.