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Article

The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking.

Journal of cell science - 1 Mar 2002

Kauppi Maria, Simonsen Anne, Bremnes Bjørn, Vieira Amandio, Callaghan Judy, Stenmark Harald, Olkkonen Vesa M

Abstract excerpt

Rab22a is a small GTPase that is expressed ubiquitously in mammalian tissues and displays the highest sequence homology to Rab5. In BHK-21 cells, overexpression of the wild-type Rab22a caused formation of abnormally large vacuole-like structures containing the early-endosomal antigen EEA1 but not Rab11, a marker of recycling endosomes or the late-endosomal/lysosomal markers LAMP-1 and lyso-bis-phosphatidic acid....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11870209
DOI: 10.1242/jcs.115.5.899

Genes

EEA1
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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