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Article

Sublocalization of Rab23, a mediator of Sonic hedgehog signaling pathway, in hepatocellular carcinoma cell lines.

Molecular medicine reports - 1 Dec 2012

Sun Hai-Ji, Liu Yun-Jian, Li Na, Sun Zhi-Yong, Zhao Hai-Wang, Wang Chen, Li Hui, Ma Fang-Ming, Shi Song-Mei, Xu Xiao-Qiu, Chen Zhe-Yu, Huang Shu-Hong

Abstract excerpt

The novel member of the Rab family of GTPases, Rab23, is an essential negative regulator of the Sonic hedgehog (Shh) signaling pathway. Loss of function mutation of the Rab23 gene causes abnormal development of the neural tube in mice and in certain human congenital diseases. The aberrant overexpression of Rab23 has been associated with various diseases, such as...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hep G2 Cells

Share to Liver Neoplasms

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Share to rab GTP-Binding Proteins

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Source

Identifiers

PMID: 23007279
DOI: 10.3892/mmr.2012.1094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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