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Article

DNA damage induces transcriptional activation of p73 by removing C-EBPalpha repression on E2F1.

Nucleic acids research - 15 Nov 2003

Marabese Mirko, Vikhanskaya Faina, Rainelli Cristina, Sakai Toshiyuki, Broggini Massimo

Abstract excerpt

p73 is a member of the p53 family often overexpressed in human cancer. Its regulation, particularly following DNA damage, is different from that of p53. Following DNA damage, we found induction of p73 at both the protein and mRNA levels. Furthermore, by using different p73 promoter fragments, we found a role for E2F1 in mediating transcription of p73. However, this observation alone does not account for the...

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Source

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Identifiers

PMID: 14602923
DOI: 10.1093/nar/gkg869
PMCID: PMC275563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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