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Article

Identification of direct p73 target genes combining DNA microarray and chromatin immunoprecipitation analyses.

The Journal of biological chemistry - 8 Nov 2002

Fontemaggi Giulia, Kela Itai, Amariglio Ninette, Rechavi Gideon, Krishnamurthy Janakiraman, Strano Sabrina, Sacchi Ada, Givol David, Blandino Giovanni

Abstract excerpt

The newly discovered p53 family member, p73, has a striking homology to p53 in both sequence and modular structure. Ectopic expression of p73 promotes transcription of p53 target genes and recapitulates the most characterized p53 biological effects such as growth arrest, apoptosis, and differentiation. Unlike p53-deficient mice that develop normally but are subject to spontaneous tumor formation, p73-deficient...

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Source

Identifiers

PMID: 12213815
DOI: 10.1074/jbc.M205573200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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