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Article

A common polymorphism in XRCC1 as a biomarker of susceptibility for chemically induced genetic damage.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jan 2000

Li Yongliang, Marion Marie-Jeanne, Rundle Andrew, Brandt-Rauf Paul W

Abstract excerpt

We have recently demonstrated a significant dose-response relationship between vinyl chloride exposure and mutant p53 biomarkers in humans. The aim of this study was to examine a common polymorphism in the DNA repair gene XRCC1 as a potential biomarker of susceptibility modifying this relationship, consistent with the known mechanism of production of p53 mutations via vinyl chloride-induced etheno-DNA adducts,...

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Source

Identifiers

PMID: 14602524
DOI: 10.1080/13547500310001619301

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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