Article
Polymorphisms of microsomal epoxide hydrolase in French vinyl chloride workers.
International journal of occupational medicine and environmental health - 1 Jan 2005
Li Yongliang, Lee Stephen, Marion Marie-Jeanne, Brandt-Rauf Paul W
Abstract excerpt
OBJECTIVES: The purpose of this study was to determine if polymorphisms in microsomal epoxide hydrolase, an enzyme involved in the metabolism of reactive intermediates of vinyl chloride (VC), contribute to the variable susceptibility to the mutagenic effects of vinyl chloride among exposed workers. MATERIALS AND METHODS: Polymorphisms at codons 113 and 139 were determined in DNA samples from 211 French vinyl...
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