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Article

BER gene polymorphisms (OGG1 Ser326Cys and XRCC1 Arg194Trp) and modulation of DNA damage due to pesticides exposure.

Environmental and molecular mutagenesis - 1 Jan 2011

Rohr Paula, da Silva Juliana, Erdtmann Bernardo, Saffi Jenifer, Guecheva Temenouga Nikolova, Antônio Pêgas Henriques João, Kvitko Kátia

Abstract excerpt

The susceptibility of individuals to the genotoxic effect of pesticides can be modulated by genetic variations in the xenobiotic detoxification and DNA repair processes. This study evaluates if the two BER polymorphisms (XRCC1Arg194Trp and OGG1Ser326Cys) or the combined genotypes of these polymorphisms with PON1Gln192Arg could modify individual susceptibility to pesticide exposure in vineyard workers, as measured...

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Source

Identifiers

PMID: 20209647
DOI: 10.1002/em.20562

Genes

PON1
OGG1
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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