Article
XRCC1 Arg399Gln genetic polymorphism in a Turkish population.
International journal of toxicology - 1 Jan 2000
Kocabaş Neslihan Aygün, Karahalil Bensu
Abstract excerpt
Humans are routinely exposed to mutagenic and carcinogenic chemicals. These chemicals can form DNA adducts in vivo and thus lead to DNA damage. The integrity of most of the so-damaged DNAs is typically restored as a consequence of the action of certain DNA-repairing enzymes. In several DNA repair genes, polymorphisms may result in reduced repair capacity, which has been implicated as a risk factor for various...
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