Article
The Pol32 subunit of DNA polymerase delta contains separable domains for processive replication and proliferating cell nuclear antigen (PCNA) binding.
The Journal of biological chemistry - 16 Jan 2004
Johansson Erik, Garg Parie, Burgers Peter M J
Abstract excerpt
We have carried out a domain analysis of POL32, the third subunit of Saccharomyces cerevisiae DNA polymerase delta (Pol delta). Interactions with POL31, the second subunit of Pol delta, are specified by the amino-terminal 92 amino acids, whereas interactions with the replication clamp proliferating cell nuclear antigen (PCNA, POL30) reside at the extreme carboxyl-terminal region. Pol32 binding, in vivo and in...
Topics
- Alleles
- Binding Sites
- DNA Polymerase I
- DNA Polymerase III
- DNA Replication
- Phenotype
- Proliferating Cell Nuclear Antigen
- Protein Subunits
- Saccharomyces cerevisiae Proteins
