Article
Loss of Pol32 in Drosophila melanogaster causes chromosome instability and suppresses variegation.
PloS one - 1 Jan 2015
Tritto Patrizia, Palumbo Valeria, Micale Lucia, Marzulli Marco, Bozzetti Maria Pia, Specchia Valeria, Palumbo Gioacchino, Pimpinelli Sergio, Berloco Maria
Abstract excerpt
Pol32 is an accessory subunit of the replicative DNA Polymerase δ and of the translesion Polymerase ζ. Pol32 is involved in DNA replication, recombination and repair. Pol32's participation in high- and low-fidelity processes, together with the phenotypes arising from its disruption, imply multiple roles for this subunit within eukaryotic cells, not all of which have been fully elucidated. Using pol32 null mutants...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
