Article
Mutations in yeast proliferating cell nuclear antigen define distinct sites for interaction with DNA polymerase delta and DNA polymerase epsilon.
Molecular and cellular biology - 1 Nov 1997
Eissenberg J C, Ayyagari R, Gomes X V, Burgers P M
Abstract excerpt
The importance of the interdomain connector loop and of the carboxy-terminal domain of Saccharomyces cerevisiae proliferating cell nuclear antigen (PCNA) for functional interaction with DNA polymerases delta (Poldelta) and epsilon (Pol epsilon) was investigated by site-directed mutagenesis. Two alleles, pol30-79 (IL126,128AA) in the interdomain connector loop and pol30-90 (PK252,253AA) near the carboxy terminus,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.