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Article

Pol32 is required for Pol zeta-dependent translesion synthesis and prevents double-strand breaks at the replication fork.

Mutation research - 1 Dec 2007

Hanna Michelle, Ball Lindsay G, Tong Amy H, Boone Charles, Xiao Wei

Abstract excerpt

POL32 encodes a non-essential subunit of Poldelta and plays a role in Poldelta processivity and DNA repair. In order to understand how Pol32 is involved in these processes, we performed extensive genetic analysis and demonstrated that POL32 is required for Polzeta-mediated translesion synthesis, but not for Poleta-mediated activity. Unlike Polzeta, inactivation of Pol32 does not result in decreased spontaneous...

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Identifiers

PMID: 17681555
DOI: 10.1016/j.mrfmmm.2007.06.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Pol32 is required for Pol zeta-dependent translesion synthesis and prevents double-strand breaks at the replication fork.PMID 17681555Read ↗

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