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Article

MCP-1-MCP-3-Eotaxin gene cluster influences HIV-1 transmission.

AIDS (London, England) - 7 Nov 2003

Modi William S, Goedert James J, Strathdee Steffanie, Buchbinder Susan, Detels Roger, Donfield Sharyne, O'Brien Stephen J, Winkler Cheryl

Abstract excerpt

BACKGROUND: MCP-1 (CCL2), MCP-3 (CCL7), and eotaxin (CCL11) are genes for CC chemokines clustered on the long arm of chromosome 17. Previous studies have implicated these chemokines in monocyte recruitment, viral replication, and anti-HIV cytotoxic T cell responses. An epidemiological analysis identified genetic variants influencing HIV-1 transmission and disease progression. METHODS: Genomic DNA from over 3000...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14571188
DOI: 10.1097/00002030-200311070-00011

Genes

CCL11
CCL2
CCL7
CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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