Article
Novel genetic associations and gene-gene interactions of chemokine receptor and chemokine genetic polymorphisms in HIV/AIDS.
AIDS (London, England) - 1 Jun 2017
Valverde-Villegas Jacqueline M, de Medeiros Rúbia M, de Andrade Karine P, Jacovas Vanessa C, Dos Santos Breno R, Simon Daniel, de Matos Almeida Sabrina E, Chies José A B
Abstract excerpt
OBJECTIVE: To investigate the influence of candidate polymorphisms on chemokine receptor/ligand genes on HIV infection and AIDS progression (HIV/AIDS). DESIGN: Fifteen polymorphisms of the CCR3, CCR4, CCR5, CCR6, CCR8, CXCR3, CXCR6, CCL20, CCL22 and CXCL10 genes were analysed in 206 HIV-positive patients classified as rapid progressors (n = 40), or nonrapid progressors (n = 166), and in 294 HIV-seronegative...
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