Article
Role of chemokines polymorphisms in diseases.
Immunology letters - 30 Jul 2012
Guergnon J, Combadière C
Abstract excerpt
The interest into chemokine polymorphisms came with the discovery of allelic variants of HIV co-receptors (CCR5 and CXCR4 mainly) that confers protection against virus entry into usual permissive cells. Since then, chemokines genetic background has been deeply studied in order to find associations between allelic variants and inflammation-related diseases as well as infectious diseases. In addition to HIV...
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