Article
Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals.
Human heredity - 1 Jan 2003
Stram Daniel O, Leigh Pearce Celeste, Bretsky Phillip, Freedman Matthew, Hirschhorn Joel N, Altshuler David, Kolonel Laurence N, Henderson Brian E, Thomas Duncan C
Abstract excerpt
The US National Cancer Institute has recently sponsored the formation of a Cohort Consortium (http://2002.cancer.gov/scpgenes.htm) to facilitate the pooling of data on very large numbers of people, concerning the effects of genes and environment on cancer incidence. One likely goal of these efforts will be generate a large population-based case-control series for which a number of candidate genes will be...
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