Article
Haplotype-based regression analysis and inference of case-control studies with unphased genotypes and measurement errors in environmental exposures.
Biometrics - 1 Sept 2008
Lobach Iryna, Carroll Raymond J, Spinka Christine, Gail Mitchell H, Chatterjee Nilanjan
Abstract excerpt
It is widely believed that risks of many complex diseases are determined by genetic susceptibilities, environmental exposures, and their interaction. Chatterjee and Carroll (2005, Biometrika 92, 399-418) developed an efficient retrospective maximum-likelihood method for analysis of case-control studies that exploits an assumption of gene-environment independence and leaves the distribution of the environmental...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
