Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maximum likelihood estimation of haplotype effects and haplotype-environment interactions in association studies.

Genetic epidemiology - 1 Dec 2005

Lin D Y, Zeng D, Millikan R

Abstract excerpt

The associations between haplotypes and disease phenotypes offer valuable clues about the genetic determinants of complex diseases. It is highly challenging to make statistical inferences about these associations because of the unknown gametic phase in genotype data. We describe a general likelihood-based approach to inferring haplotype-disease associations in studies of unrelated individuals. We consider all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Breast Neoplasms
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Haplotypes

Share to Likelihood Functions

Share to Linkage Disequilibrium

Share to Regression Analysis

Source

Identifiers

PMID: 16240443
DOI: 10.1002/gepi.20098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maximum likelihood estimation of haplotype effects and haplotype-environment interactions in association studies.PMID 16240443Read ↗

Efficient semiparametric estimation of haplotype-disease associations in case-cohort and nested case-control studies.Semantic proximity Read ↗

A general framework for studying genetic effects and gene-environment interactions with missing data.Semantic proximity Read ↗

Estimating haplotype-disease associations with pooled genotype data.Semantic proximity Read ↗

Haplotype-based association analysis in cohort studies of unrelated individuals.Semantic proximity Read ↗

Statistically efficient association analysis of quantitative traits with haplotypes and untyped SNPs in family studies.Semantic proximity Read ↗

Haplotype association analysis of human disease traits using genotype data of unrelated individuals.Semantic proximity Read ↗

Multi-SNP haplotype analysis methods for association analysis.Semantic proximity Read ↗

Multi-SNP Haplotype Analysis Methods for Association Analysis.Semantic proximity Read ↗

Conditional likelihood inference in a case- cohort design: an application to haplotype analysis.Semantic proximity Read ↗

Simple and efficient analysis of disease association with missing genotype data.Semantic proximity Read ↗

Statistical analysis for haplotype-based matched case-control studies.Semantic proximity Read ↗

Multinomial logistic regression approach to haplotype association analysis in population-based case-control studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.