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Article

Discs-Large and Strabismus are functionally linked to plasma membrane formation.

Nature cell biology - 1 Nov 2003

Lee Ok-Kyung, Frese Kristopher K, James Jennifer S, Chadda Darshana, Chen Zhi-Hong, Javier Ronald T, Cho Kyung-Ok

Abstract excerpt

During early embryogenesis in Drosophila melanogaster, extensive vesicle transport occurs to build cell boundaries for 6,000 nuclei. Here we show that this important process depends on a functional complex formed between the tumour suppressor and adaptor protein Discs-Large (Dlg) and the integral membrane protein Strabismus (Stbm)/Van Gogh (Vang). In support of this idea, embryos with mutations in either dlg or...

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Identifiers

PMID: 14562058
DOI: 10.1038/ncb1055
PMCID: PMC3471657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Discs-Large and Strabismus are functionally linked to plasma membrane formation.PMID 14562058Read ↗

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